Cover [Abstract] Document Type Document Type Amendment Flag Amendment Flag Document Quarterly Report Document Period End Date Document Period End Date Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal Period Focus Trading Symbol Trading Symbol Entity Registrant Name Entity Registrant Name Entity Central Index Key Entity Central Index Key Current Fiscal Year End Date Current Fiscal Year End Date Entity Current Reporting Status Entity Current Reporting Status Entity Filer Category Entity Filer Category Entity Small Business Entity Small Business Entity Emerging Growth Company Entity Emerging Growth Company Entity Shell Company Entity Shell Company Entity Common Stock Shares Outstanding Entity Common Stock, Shares Outstanding Entity Interactive Data Current Entity Interactive Data Current Security12b Title Title of 12(b) Security Security Exchange Name Security Exchange Name Entity File Number Entity File Number Entity Incorporation State Country Code Entity Incorporation, State or Country Code Entity Tax Identification Number Entity Tax Identification Number Entity Address Address Line1 Entity Address, Address Line One Entity Address Address Line2 Entity Address, Address Line Two Entity Address City Or Town Entity Address, City or Town Entity Address State Or Province Entity Address, State or Province Entity Address Postal Zip Code Entity Address, Postal Zip Code City Area Code City Area Code Local Phone Number Local Phone Number Document Transition Report Document Transition Report CONSOLIDATED BALANCE SHEETS Assets [Abstract] ASSETS Assets Current [Abstract] Current assets: Cash And Cash Equivalents At Carrying Value Cash and cash equivalents Restricted Cash Current Restricted cash Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Cash, cash equivalents and restricted cash at end of period Cash, cash equivalents and restricted cash at beginning of period Total cash, cash equivalents and restricted cash Short Term Investments Short-term investments Accounts Receivable Gross Current Accounts receivable Carrying amount due within one year of the balance sheet date (or one operating cycle, if longer) from tax authorities as of the balance sheet date representing refunds of overpayments or recoveries based on agreed-upon resolutions of disputes and research & development incentives. Income Taxes and Research & Development Incentive Receivable, Current Income tax and R&D incentive receivables Prepaid Expense And Other Assets Current Prepaid expenses and other current assets Assets Current Total current assets Property Plant And Equipment Net Property and equipment, net Intangible Assets Net Excluding Goodwill Intangible assets, net Other Assets Noncurrent Other assets Assets Total assets Liabilities And Stockholders Equity [Abstract] LIABILITIES AND STOCKHOLDERS' EQUITY Liabilities Current [Abstract] Current liabilities: Accounts Payable Current Accounts payable Business Combination, Contingent Consideration, Liability, Current Contingent consideration Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Also includes the aggregate carrying amount, as of the balance sheet date, of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered and of liabilities not separately disclosed in the balance sheet. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Accrued Expenses And Other Current Liabilities Accrued expenses and other current liabilities Total accrued expenses and other current liabilities Liabilities Current Total current liabilities Other Long Term Debt Noncurrent Other long-term liabilities Liabilities Total liabilities Commitments And Contingencies Commitments and contingencies (Note 14) Stockholders Equity [Abstract] Stockholders' equity: Common Stock Value Common stock, $0.0001 par value; 200,000,000 shares authorized; 49,161,637 and 40,993,768 shares issued and outstanding as of September 30, 2022 and December 31, 2021, respectively Additional Paid In Capital Additional paid-in capital Retained Earnings Accumulated Deficit Accumulated deficit Accumulated Other Comprehensive Income Loss Net Of Tax Accumulated other comprehensive loss, net Stockholders Equity Ending Balance Beginning Balance Total stockholders' equity Liabilities And Stockholders Equity Total liabilities and stockholders' equity Common Stock Par Or Stated Value Per Share Common stock, par or stated value per share Common stock, par or stated value per share Common Stock Shares Authorized Common stock, shares authorized Common Stock Shares Issued Common stock, shares issued Common Stock Shares Outstanding Common stock, shares outstanding CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS Revenue From Contract With Customer Excluding Assessed Tax Revenues Operating Expenses [Abstract] Operating expenses: Research And Development Expense Research and development General And Administrative Expense General and administrative Impairment of Long-Lived Assets Held-for-use Impairment loss on construction-in-progress Non-cash impairment charge Operating Expenses Total operating expenses Operating Income Loss Loss from operations Nonoperating Income Expense [Abstract] Other income (expense): Interest Expense Interest expense Investment Income Interest Interest income Other Nonoperating Income Expense Other income (expense), net Nonoperating Income Expense Total other income (expense), net Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest Net loss before income taxes Income Tax Expense Benefit Income tax benefit Income tax benefit Net Income Loss Net loss Net loss Other Comprehensive Income Loss Available For Sale Securities Adjustment Net Of Tax Other comprehensive income - unrealized (loss) gain on short-term investments Unrealized (loss) gain on short-term investments Comprehensive Income Net Of Tax Including Portion Attributable To Noncontrolling Interest Comprehensive loss Net loss per share, basic Net loss per share, diluted Weighted Average Number Of Share Outstanding Basic And Diluted Weighted-average common shares outstanding, basic Weighted Average Number of Shares Outstanding, Diluted Weighted-average common shares outstanding, diluted CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY Statement [Table] Statement [Table] Statement Equity Components [Axis] Equity Component Common Stock [Member] Additional Paid-In Capital [Member] Accumulated Deficit [Member] Accumulated Other Comprehensive Loss [Member] Statement [Line Items] Statement [Line Items] Shares Outstanding Ending Balance (in shares) Beginning Balance (in shares) Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value Stock-based compensation Stock Issued During Period Value Stock Options Exercised Exercise of stock options Stock Issued During Period Shares Stock Options Exercised Exercise of stock options (in shares) Restricted Stock Value Shares Issued Net Of Tax Withholdings Vesting of restricted stock awards including withholding, net Restricted Stock Shares Issued Net Of Shares For Tax Withholdings Unrestricted common stock Vesting of restricted stock awards including withholding, net (in shares) Stock Issued During Period Value Employee Stock Purchase Plan Issuance of common stock from Employee Stock Purchase Plan Employees purchased, value Stock Issued During Period Shares Employee Stock Purchase Plans Issuance of common stock from Employee Stock Purchase Plan (in shares) Employees purchased, shares Stock Issued During Period Value New Issues Issuance of common stock in at the market offerings, net Stock Issued During Period Shares New Issues Issuance of common stock in at the market offerings, net (in shares) Shares of common stock sold Retirement of common stock in exchange for common stock warrant. Retirement Of Common Sock In Exchange For Common Stock Warrant Retirement of common stock in exchange for common stock warrant Retirement of common stock in exchange for common stock warrant shares. Retirement Of Common Sock In Exchange For Common Stock Warrant Shares Retirement of common stock in exchange for common stock warrant (in Shares) Issuance of common stock warrant in exchange for retirement of common stock. Issuance Of Common Stock Warrant In Exchange For Retirement Of Common Stock Issuance of common stock warrant in exchange for retirement of common stock Stock Issued During Period Value Acquisitions Issuance of common stock related to contingent consideration liability Stock Issued During Period Shares Acquisitions Issuance of common stock related to contingent consideration liability (in shares) Stock issued during period value exercise of warrants. Stock Issued During Period Value Exercise Of Warrants Issuance of common stock upon cashless exercise of warrants Stock issued during period share exercise of warrants. Stock Issued During Period Share Exercise Of Warrants Issuance of common stock upon cashless exercise of warrants (in shares) Stock Issued During Period, Shares, Other Other increase (in shares) CONSOLIDATED STATEMENTS OF CASH FLOWS Net Cash Provided By Used In Operating Activities [Abstract] CASH FLOWS FROM OPERATING ACTIVITIES: Profit Loss Net loss Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Business Combination Contingent Consideration Arrangements Change In Amount Of Contingent Consideration Liability1 Change in fair value Change in fair value of contingent consideration liability Change in value of contingent consideration for acquired in-process research and development Share Based Compensation Stock-based compensation expense Depreciation Depletion And Amortization Depreciation and amortization Foreign Currency Transaction Gain Loss Unrealized Unrealized (gains) losses on foreign currency exchange Increase Decrease In Operating Capital [Abstract] Changes in operating assets and liabilities: Increase Decrease In Accounts Receivable Accounts receivable Increase Decrease In Prepaid Deferred Expense And Other Assets Prepaid expenses and other assets Increase Decrease In Accounts Payable Accounts payable Increase Decrease In Accrued Liabilities And Other Operating Liabilities Accrued expenses and other liabilities The increase (decrease) during the reporting period in income taxes receivable, which represents the amount due from tax authorities for refunds of overpayments or recoveries of income taxes paid. Increase (Decrease) in Income Taxes and Tax Incentive Receivable Income tax and R&D incentive receivables Net Cash Provided By Used In Operating Activities Net cash used in operating activities Net Cash Provided By Used In Investing Activities [Abstract] CASH FLOWS FROM INVESTING ACTIVITIES: Proceeds From Sale And Maturity Of Available For Sale Securities Proceeds from sales and maturities of short-term investments Payments To Acquire Available For Sale Securities Debt Purchases of short-term investments Payments To Acquire Property Plant And Equipment Purchases of property and equipment, net Payments To Acquire Intangible Assets Cash paid for internally developed patents Net Cash Provided By Used In Investing Activities Net cash (used in) provided by investing activities Net Cash Provided By Used In Financing Activities [Abstract] CASH FLOWS FROM FINANCING ACTIVITIES: Payments of deferred offering costs. Payments Of Deferred Offering Costs Payments of deferred offering costs Proceeds From Issuance Of Common Stock Proceeds from issuance of common stock in at-the-market offerings, net Proceeds from issuance of common stock in public offering Proceeds From Stock Plans Proceeds from issuance of common stock from Employee Stock Purchase Plan Proceeds from Stock Options Exercised Proceeds from exercises of stock options, net Net Cash Provided By Used In Financing Activities Net cash provided by financing activities Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect Net (decrease) increase in cash and cash equivalents and restricted cash Cash Flow Noncash Investing And Financing Activities Disclosure [Abstract] SUPPLEMENTAL NON-CASH ACTIVITIES: Common stock issued related to contingent consideration liability. Common Stock Issued Related To Contingent Consideration Liability Common stock issued related to contingent consideration liability Operating lease liability and right of use asset addition. Addition Operating Lease Liability And Right Of Use Asset Operating lease liability and right of use asset addition Nature of Business and Basis of Presentation Nature of Business and Basis of Presentation. Nature of Business and Basis of Presentation Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies Fair Value Measurements Fair Value Disclosures [Text Block] Fair Value Measurements Operating Leases Lessee Operating Leases [Text Block] Operating Leases Accrued Expenses Accounts Payable And Accrued Liabilities Disclosure [Text Block] Accrued Expenses Contingent Consideration Business Combination Disclosure [Text Block] Contingent consideration Other Long-Term Liabilities Other Liabilities Disclosure [Text Block] Other Long-Term Liabilities Common Stock The entire disclosure of common stock. Common Stock [Text Block] Common Stock Warrants Stockholders Equity Note Disclosure [Text Block] Warrants Stock-Based Compensation Disclosure Of Compensation Related Costs Share Based Payments [Text Block] Stock-Based Compensation U.S. government contracts and grants disclosures abstract. U.S. Government Contracts and Grants U.S. government contracts and grants. U S Government Contracts And Grants [Text Block] U.S. Government Contracts and Grants Income Taxes Income Tax Disclosure [Text Block] Income Taxes Net Loss Per Share Earnings Per Share [Text Block] Net Loss Per Share Commitments And Contingencies. Commitments And Contingencies Disclosure [Text Block] Commitments and Contingencies Use Of Estimates Use of Estimates Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Table [Text Block] Schedule of Fair Value Assets and Liabilities Measured on Recurring Basis Schedule Of Available For Sale Securities Reconciliation Table [Text Block] Schedule of Short Term Investments Schedule of supplemental balance sheet information related to Operating leases. Schedule Of Supplemental Balance Sheet Information Related To Operating Leases Table [Text Block] Summary of Supplemental other Information Related to Operating Leases Balance Sheet Schedule Of Accrued Liabilities Table [Text Block] Schedule of Accrued Expenses and Other Current Liabilities Schedule Of Business Acquisitions By Acquisition Contingent Consideration [Text Block] Summary of Fair Value of Contingent Consideration Other Noncurrent Liabilities Table [Text Block] Summary of Other Long-Term Liabilities Schedule Of Stockholders Equity Note Warrants Or Rights [Text Block] Summary of Warrant Activity Schedule Of Other Share Based Compensation Activity Table [Text Block] Schedule of Information Related to Stock Options Outstanding Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Text Block] Schedule of Stock-based Compensation Expense Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Cash And Cash Equivalents [Axis] Cash and Cash Equivalents Money Market Funds [Member] Fair Value By Measurement Frequency [Axis] Measurement Frequency Fair Value, Measurements, Recurring [Member] Fair Value By Fair Value Hierarchy Level [Axis] Fair Value Hierarchy and NAV Level 1 [Member] Level 2 [Member] Level 3 [Member] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Investments Fair Value Disclosure Cash equivalents Assets Fair Value Disclosure Total Business Combination Contingent Consideration Liability Ending balance Beginning balance Estimated future contingent consideration Contingent consideration liability (see Note 6) Liabilities Fair Value Disclosure Total Debt Securities Available For Sale [Table] Debt Securities Available For Sale [Table] Financial Instrument [Axis] Financial Instruments United States Treasury Securities [Member] Commercial Paper And Corporate Debt Securities [Member]. Commercial Paper and Corporate Debt Securities [Member] Asset Backed Securities [Member] Schedule Of Available For Sale Securities [Line Items] Schedule Of Available For Sale Securities [Line Items] Available For Sale Debt Securities Amortized Cost Basis Amortized Cost Debt Securities Available For Sale Accumulated Gross Unrealized Gain Loss Before Tax Unrealized Loss Available For Sale Securities Debt Securities Market Value Counterparty Name [Axis] Counterparty Name Lonza manufacturing agreement member Lonza Manufacturing Agreement [Member] Property Plant And Equipment By Type [Axis] Long-Lived Tangible Asset Construction-In-Progress Fair Value, Nonrecurring [Member] Assets or liabilities that were measured at fair value on a non-recurring basis. Assets Or Liabilities Measured At Fair Value On Non Recurring Basis Assets or liabilities measured at fair value on a non-recurring basis. Property, Plant, and Equipment, Fair Value Disclosure Fair value of impaired assets Commitment to procure equipment and construction Commitment To Procure Equipment And Construction Property, Plant and Equipment, Additions Capitalized costs Operating Lease Payments Cash paid for operating lease liabilities Operating lease rent expense Operating Lease Liability Operating lease obligations (see Note 5 and 7) Operating Lease Right Of Use Asset Operating lease right-of-use assets (included in "Other assets" in Balance Sheet) Operating Lease Weighted Average Remaining Lease Term1 Weighted-average remaining lease term (years) Operating Lease Weighted Average Discount Rate Percent Weighted-average discount rate Accrued Liabilities And Other Liabilities [Abstract] Accrued Professional Fees Current Accrued professional services Employee Related Liabilities Current Accrued payroll and employee benefits Accrued research and development. Accrued Research And Development Accrued research and development Operating Lease Liability Current Lease obligation, current portion (see Note 4) Accrued Income Taxes, Current Income tax payable Accrued Liabilities and Other Liabilities Accrued interest and other Schedule Of Business Acquisitions By Acquisition [Table] Schedule Of Business Acquisitions By Acquisition [Table] Business Acquisition [Axis] Business Acquisition, Acquiree Spitfire Pharma, Inc. Spitfire Pharma, Inc. [Member] Subsidiary Sale Of Stock [Axis] Sale of Stock Clinical trial notification. Clinical Trial Notification [Member] Range [Axis] Statistical Measurement Maximum [Member] Contingent Consideration By Type [Axis] Contingent Consideration Type Investigational New Drug Application milestone. Investigational New Drug Application Milestone [Member] Investigational New Drug Application and Regulatory milestones. Investigational New Drug Application and Regulatory Milestones [Member] Sales milestone. Sales Milestones [Member] Regulatory milestone. Regulatory Milestones [Member] Phase 2 Milestone Phase Two Milestone [Member] Business Acquisition [Line Items] Business Acquisition [Line Items] Business Acquisition Date Of Acquisition Agreement1 Agreement date Business Acquisition Equity Interests Issued Or Issuable Number Of Shares Issued Unregistered shares of common stock Payments To Acquire Businesses Gross Up-front consideration Business combination contingent consideration payment term. Business Combination Contingent Consideration Payment Term Estimated future contingent consideration term Business acquisition term of license agreement. Business Acquisition Term Of License Agreement License agreement term License agreement term Number of consecutive trading days. Number Of Consecutive Trading Days Number of consecutive trading days Business Acquisition Share Price Consideration amount Percentage of shares that will be issued upon satisfaction of the milestones that are subject to lock-up period of three months. Contingent Consideration, Percentage Of Shares Release After Three Months Contingent consideration, percentage of shares released after three months Percentage of shares that will be issued upon satisfaction of the milestones that are subject to lock-up period of six months. Contingent Consideration, Percentage Of Shares Release After Six Months Contingent consideration, percentage of shares released after six months Shares issued for contingent milestone payment. Shares Issued For Contingent Milestone Payment Shares issued for contingent milestone payment Period for submission of clinical trial notification. Period For Submission Of Clinical Trial Notification Period for submission of clinical trial notification Submission date of clinical trial notification. Submission Date Of Clinical Trial Notification Submission date of clinical trial notification Business Combination Consideration Transferred Equity Interests Issued And Issuable Fair value of payments settled in common stock (Phase II Milestone) Amount of research and development incentive credit. Research and Development Incentive Credit Research and development incentive credit Amount of research and development incentive credit earned. Research and Development Incentive Credit Earned Research and development incentive credit earned Operating Lease Liability Noncurrent Lease obligation, long-term portion (see Note 4) Economic conditional incentive grants. Economic Conditional Incentive Grants Conditional economic incentive grants Other Liabilities Noncurrent Other Long Term Debt Noncurrent Total other long-term liabilities Schedule Of Stock By Class [Table] Schedule Of Stock By Class [Table] Public Offering [Member] Over-Allotment Option [Member] At-the-market offering. At-The-Market Offering [Member] Exchange Warrants [Member]. Exchange Warrants [Member] Class Of Warrant Or Right [Axis] Class of Warrant or Right Pre-funded warrants. Pre-Funded Warrants [Member] Type Of Arrangement [Axis] Collaborative Arrangement and Arrangement Other than Collaborative Equity Distribution Agreement. Equity Distribution Agreement [Member] Piper Sandler company and evercore group limited liability company and B Riley Securities inc Member. Piper Sandler company and evercore group limited liability company and B Riley Securities inc [Member] Ownership [Axis] Ownership [Domain] Represent the information pertaining to investors and its affiliates (the Exchanging Stockholders). Exchanging Stockholders [Member] Changes In Equity And Comprehensive Income Line Items [Line Items] Changes In Equity And Comprehensive Income Line Items [Line Items] Changes In Equity And Comprehensive Income Line Items [Line Items] Shares Issued Price Per Share Public offering price, per share Class Of Warrant Or Right Number Of Securities Called By Warrants Or Rights Number of securities called by warrants or rights Class Of Warrant Or Right Outstanding Warrants outstanding, September 30, 2022 Warrants outstanding, December 31, 2021 Warrants outstanding Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1 Exercise price of warrants or rights Weighted Average Exercise Price Class of warrant or right, issuance price per warrant or right. Class Of Warrant Or Right Issuance Price Per Warrant Or Right Purchase price of warrants issued Ownership percentage on exercise of warrants without notice, minimum. Ownership Percentage On Exercise Of Warrants Without Notice Minimum Ownership percentage on exercise of warrants without notice, minimum Ownership percentage on exercise of warrants with notice, maximum. Ownership Percentage On Exercise Of Warrants With Notice Maximum Ownership percentage on exercise of warrants with notice, maximum Notice period to increase ownership percentage on exercise of warrants. Notice Period To Increase Ownership Percentage On Exercise Of Warrants Notice period to increase ownership percentage on exercise of warrants Proceeds From Issuance Or Sale Of Equity Gross proceeds from offering including exercise of underwriter's option Aggregate offering price. Aggregate Offering Price Aggregate offering price Payments Of Stock Issuance Costs Issuance costs Deferred offering costs applied to the proceeds. Deferred Offering Costs Applied To The Proceeds Commission and other offering costs The number of shares exchanged for pre-funded warrants. Stock Exchanged For Pre Funded Warrants Common stock exchanged for pre-funded warrants Number of warrants exercised. Number Of Warrants Exercised Number of warrants exercised Common Stock Capital Shares Reserved For Future Issuance Remaining shares available for issuance Noncontrolling Interest, Ownership Percentage by Noncontrolling Owners Ownership percentage Class Of Warrant Or Right [Table] Class Of Warrant Or Right [Line Items] Number of warrants expired. Warrants Expired Expired Number of warrants exercised for conversion of securities. Number Of Warrants Exercised For Conversion Of Securities Exercises (see Note 8) Warrants and Rights Outstanding, Term Weighted-Average Remaining Contractual Term (Years) Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Award Type [Axis] Award Type Stock Options [Member] Restricted Stock [Member] Restricted Stock Units [Member] Plan Name [Axis] Plan Name Two thousand and nineteen employee stock purchase plan. 2019 Employee Stock Purchase Plan [Member] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Shares granted Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Weighted Average Grant Date Fair Value Weighted average grant date fair value Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Period1 Vesting Period Sharebased Compensation Arrangement By Sharebased Payment Award Expiration Period Stock option expiration Period Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Stock Options Unrecognized compensation cost, stock options Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross Number of Stock Options, Granted Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price Stock options granted, weighted-average exercise price Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value Weighted-average grant date fair value of stock options granted Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number Unvested restricted stock, shares Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Share Based Awards Other Than Options Unrecognized compensation expense Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1 Unrecognized stock-based compensation expense, period for recognition Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Number of share vested Share-based Payment Arrangement, Shares Withheld for Tax Withholding Obligation Common stock withheld to satisfy tax withholding obligations. Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number Number of Stock Options, Outstanding Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number Number of Stock Options, Exercisable Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Number Of Shares Number of Stock Options, Unvested Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price Weighted-average Exercise Price, Outstanding Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price Weighted-average Exercise Price, Exercisable Share based compensation arrangement by share based payment award options unvested outstanding weighted average exercise price. Share Based Compensation Arrangement By Share Based Payment Award Options Unvested Outstanding Weighted Average Exercise Price Weighted-average Exercise Price, Unvested Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2 Weighted-average Remaining Contractual Term, Outstanding Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1 Weighted-average Remaining Contractual Term, Exercisable Share based compensation arrangement by share based payment award options unvested outstanding weighted average remaining contractual term. Share Based Compensation Arrangement By Share Based Payment Award Options Unvested Outstanding Weighted Average Remaining Contractual Term Weighted-average Remaining Contractual Term, Unvested Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value Aggregate Intrinsic Value, Outstanding Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1 Aggregate Intrinsic Value, Exercisable Share based compensation arrangement by share based payment award options nonvested outstanding intrinsic value. Share Based Compensation Arrangement By Share Based Payment Award Options Nonvested Outstanding Intrinsic Value Aggregate Intrinsic Value, Unvested Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Income Statement Location [Axis] Income Statement Location Research and Development [Member] General and Administrative [Member] Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Allocated Share Based Compensation Expense Stock based compensation expense Product Or Service [Axis] Product and Service Grant [Member] Investment Performance [Member] Medical Technology Enterprise Consortium collaborative arrangement. MTEC Collaborative Arrangement [Member] BARDA Contract [Member]. BARDA Contract [Member] Minimum [Member] Duration of contract. Duration Of Contract Duration of contract Purchase Commitment Remaining Minimum Amount Committed Amount used to fund clinical development Government Contract Receivable Additional funding for development and manufacturing activities Other Tax Expense (Benefit) Income tax benefit due to valuation allowance Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis] Antidilutive Securities, Name Common Stock Warrants [Member] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount Antidilutive securities excluded from computation of earnings per share Commitments and contingencies. Commitments And Contingencies [Table] Commitments And Contingencies [Table] Commitments and contingencies. Commitments And Contingencies [Line Items] Commitments And Contingencies [Line Items]